Chou, Ho-Hsuan
Associate Professor
✉ Email：hohsuan@ncku.edu.tw
☎ Phone：06-2757575-65350
Organic Chemistry
Education
PhD in Chemistry, National Tsing Hua University (2014)
Experience
2016-2022 National Cheng Kung University, Assistant Professor
2022-Present National Cheng Kung University, Associate Professor
Publications
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Kuo, Y. Y.; Pen, S. Y.; Cheng, C. H.; Ho, W. C.; Chen, C. Y.; Wu, W. C.; ... & Chou, H. H. “Decrease of KATP channel expression through D3 receptor-mediated GSK3β signaling alleviates levodopa-induced dyskinesia (LID) in Parkinson's disease mouse model.” Life Sci., 2024, 359, 123255.
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Akbarian, M.; Chen, I. N.; Lu, P. H.; Do, Q. T.; Tzeng, S. F.; Chou, H. H.; & Chen, S. H.* “Chaperone/Polymer Complexation of Protein-Based Fluorescent Nanoclusters against Silica Encapsulation-Induced Physicochemical Stresses.” Biomacromolecules, 2024 25 (10), 6515-6525
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Chi, T. C.; Yang, P. C.; Hung, S.K.; Wu, H.W.; Wang, H.C.; Liu, H.K.; Liu, L.W. and Chou, H.H.* "Synthesis of Multisubstituted 1,2,3-Triazoles: Regioselective Formation and Reaction Mechanism" J. Org. Chem. 2024, 89, 8, 5401–5408
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Huang, W.C.; Huang, L.J.; Hsu, L.S.; Huang, S.T.; Lo, W.T.; Wang, T.F.; Sun, W.T.; Wei, W.Y.; Lee, Y.S.; Chuang, S.H.; Lee, C.P.; Chou, H.H.*; Chen, S.H.* "Selective and predicable amine conjugation sites by kinetic characterization under excess reagents" Scientific Reports, 2021, 11, 21222.
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Lu, G. H.; Huang, T. C.; Hsueh, H. C.; Yang, S. C.; Cho, T. W.; Chou, H. H.* "Novel N-Transfer Reagent for Converting α-Amino Acid Derivatives to α-Diazo Compounds" Chem. Commun., 2021, 57, 4839-4842.
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Jhan, S. Y.; Huang, L. J.; Wang, T. F.; Chou, H. H.; Chen, S. H.* "Dimethyl Labeling Coupled with Mass Spectrometry for Topographical Characterization of Primary Amines on Monoclonal Antibodies" Anal. Chem., 2017, 89, 4255-4263.
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Hsu, C. S.; Chou, H. H.; Fang, J. M.* "A short synthesis of (±)-antroquinonol in an unusual scaffold of 4-hydroxy-2-cyclohexenone" Org. Biomol. Chem., 2015, 13, 5510-5519.
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Chou, H. H.; Raines, R. T.* "Conversion of azides into diazo compounds in water" J. Am. Chem. Soc., 2013, 135, 14936-14939.
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Ramu, R.; Chang, C. W.; Chou, H. H.; Wu, L. L.; Chiang, C. H.; Yu, S. S. F.* "Regio-selective hydroxylation of gem-difluorinated octanes by alkane hydroxylase(AlkB)" Tetrahedron Lett., 2011, 52, 2950-2953.
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Wu, L. L.; Yang, C. L.; Lo, F. C.; Chiang, C. H.; Chang, C. W.; Ng, K. Y.; Chou, H. H.; Hung, H. Y.; Chan, S. I.; Yu, S. S. F.* "Tuning the regio- and stereoselectivity of C-H activation in n-octanes by cytochrome P450 BM-3 with fluorine substituents: Evidence for interactions between a C-F bond and aromatic π systems" Chem. Eur. J., 2011, 17, 4774-4787.